Capillogain® Tonic

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israelite
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Re: Capillogain® Tonic

Post by israelite » Tue Dec 11, 2012 10:21 am

SyntheseLabRat wrote:oppenheimer

the problem is that it won´t be very much cheaper without the ingredients.
The costs for production, sales tax, fraction for distributors and so on won´t change much I am afraid.

Sorry, I am not allowed to tell you the concentration of Triaminodil in Capillogain Tonic.
please make some vehicles! it' worth it. if it only cost 20 dollars for a very good vehicle many people will buy it.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 11, 2012 10:29 am

We are currently sold out at amazon. It is due to a delay in the production of the Procyanidin-B3. It will be available again soon.
You can contact me here advisor@functional-products.net .
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Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by tinytim » Tue Dec 11, 2012 10:38 am

hi synth are orders from your site still available as i have already ordered yesterday two bottles?

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 11, 2012 10:40 am

tinytim wrote:hi synth are orders from your site still available as i have already ordered yesterday two bottles?
I think so, but our own depot will be sold out soon, too. But we will produce the next batch this week. I just inform you so you are not surprised that Capillogain can´t be found at amazon at the moment.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by oppenheimer82 » Tue Dec 11, 2012 11:20 am

SyntheseLabRat wrote:oppenheimer

the problem is that it won´t be very much cheaper without the ingredients.
The costs for production, sales tax, fraction for distributors and so on won´t change much I am afraid.

Sorry, I am not allowed to tell you the concentration of Triaminodil in Capillogain Tonic.
no problem, just release it. you have no idea how many people will buy your vehicles. a lot. release it and you will make a million dollars in no time.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 11, 2012 11:42 am

oppenheimer82 wrote:
SyntheseLabRat wrote:oppenheimer

the problem is that it won´t be very much cheaper without the ingredients.
The costs for production, sales tax, fraction for distributors and so on won´t change much I am afraid.

Sorry, I am not allowed to tell you the concentration of Triaminodil in Capillogain Tonic.
no problem, just release it. you have no idea how many people will buy your vehicles. a lot. release it and you will make a million dollars in no time.
You forgot the encapsulation process. After the vesicles are formed it is harder to get the ingredients inside the vesicles. It is not just like tossing stuff together.
However, a fraction of the ingredients, which you will toss in, will diffuse into the vesicles. In addition there is a publication which shows that the vesicles we use also facilitate the penetration of the non-encapsulated fraction. So it would not be useless to use our vehicle for your mix but less effective than a product obtained from a whole encapsulation process.

We will think about it.

However, you should not underestimate the ingredients in Capillogain Tonic.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by tinytim » Wed Dec 12, 2012 6:37 am

Hi fred do you massage the cap into scalp or just spread over scalp also is it runny or thick lotion?

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Re: Capillogain® Tonic

Post by Jacob » Wed Dec 12, 2012 7:45 am

israelite wrote:
Jacob wrote:
israelite wrote:
my thought with capillogain : this is the best liquid vehicle i have EVER used. within one min it dries and its like u never applied anything! this is one of the major problems with topicals they never reach the hair follicle roots and this product 100% does!
Why do you think I kept bringing up lipo/nano-type tech in the private forum :x Even if something is supposed to work w/out it...for something as hard to treat as MPB- every little extra boost can help.
THIS!, i learned my lesson! that why i like capillogain! thats why Elishalom Yechiel, Ph.D is going to make a super hairline topical. i still like proxiphen from dr proctor(phd, md)
I received mine yesterday. The stuff sure is packaged good...good enough to get to the moon and back. It is nice to apply- absorbs well. I'm applying it to a fairly dry scalp..don't know if that issue has been covered here. I say that because Elsom's can be applied to a damp scalp, and in fact Dr. Y recommends spreading it around with a bit of water, if necessary.

So Mark, Elsom's is not going to be like this product. Theirs will be thicker and won't seem to absorb quite as well- you have to spread it around and the colors will be darker or brighter and may show on the scalp. But they do absorb well..as well 8)

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Wed Dec 12, 2012 8:19 am

tinytim wrote:Hi fred do you massage the cap into scalp or just spread over scalp also is it runny or thick lotion?
Massage it in a bit.
It is liquid and therefore maybe a bit "runny", but since it absorbs very fast it is not much of a problem.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by israelite » Wed Dec 12, 2012 8:26 am

my thought with capillogain : this is the best liquid vehicle i have EVER used. within one min it dries and its like u never applied anything! this is one of the major problems with topicals they never reach the hair follicle roots and this product 100% does![/quote]

Why do you think I kept bringing up lipo/nano-type tech in the private forum :x Even if something is supposed to work w/out it...for something as hard to treat as MPB- every little extra boost can help.[/quote]
THIS!, i learned my lesson! that why i like capillogain! thats why Elishalom Yechiel, Ph.D is going to make a super hairline topical. i still like proxiphen from dr proctor(phd, md)[/quote]

I received mine yesterday. The stuff sure is packaged good...good enough to get to the moon and back. It is nice to apply- absorbs well. I'm applying it to a fairly dry scalp..don't know if that issue has been covered here. I say that because Elsom's can be applied to a damp scalp, and in fact Dr. Y recommends spreading it around with a bit of water, if necessary.

So Mark, Elsom's is not going to be like this product. Theirs will be thicker and won't seem to absorb quite as well- you have to spread it around and the colors will be darker or brighter and may show on the scalp. But they do absorb well..as well 8)[/quote]
this product aborbs very well. i'm gonna buy more and put compounds in it.

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Re: Capillogain® Tonic

Post by tinytim » Wed Dec 12, 2012 10:31 am

any news on the capillogain shampoo and will it contain l sulphate which i hope it will not,i forgot had to edit any thoughts on using some polysorbate 80 before washing hair and then apply cap when scalps dry.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Wed Dec 12, 2012 5:21 pm

tinytim wrote:any news on the capillogain shampoo and will it contain l sulphate which i hope it will not,i forgot had to edit any thoughts on using some polysorbate 80 before washing hair and then apply cap when scalps dry.
The Shampoo is planned to be produced in the first week of January, sorry for the delay.
The INCI list of Capillogain Shampoo is:
AQUA
DISODIUM LAURETH SULFOSUCCINATE
COCAMIDOPROPYL BETAINE
PEG-200 HYDROGENATED GLYCERYL PALMATE
PEG-7 GLYCERYL COCOATE
ALCOHOL DENAT.
POLYSORBATE 20
SANGUISORBA OFFICINALIS ROOT EXTRACT
PYRROLIDINIL DIAMINOPYRIMIDINE OXIDE (Triaminodil)
CAMELLIA SINENSIS LEAF EXTRACT (EGCG from Green Tea Extract)
GRAPE SEED EXTRACT
PANAX GINSENG BERRY EXTRACT
PHENOXYETHANOL
PANTHENOL
ARGININE
TAURINE
CYANOCOBALAMIN
BIOTIN

Maybe CARNITINE is added if it does not interfere with the vehicle.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Jacob » Wed Dec 12, 2012 6:25 pm

What's your opinion on those plant stem cell ingredients?.. already encapsulated is how they come. Maybe they can be obtained non-encapsulated :-k

I've always been interested in a monolaurin-based shampoo. I think we had a discussion at Regrowth about it. Maybe even in a topical...

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Re: Capillogain® Tonic

Post by tinytim » Thu Dec 13, 2012 3:29 am

fred and others have you heard of german product activogland which contains rhodanide as i got some from a german apo i have posted on general page but i will give you some info here as well www.rhodanide.com

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Thu Dec 13, 2012 3:54 am

Jacob wrote:What's your opinion on those plant stem cell ingredients?.. already encapsulated is how they come. Maybe they can be obtained non-encapsulated :-k

I've always been interested in a monolaurin-based shampoo. I think we had a discussion at Regrowth about it. Maybe even in a topical...
I remember you brought monolaurin to my attention. However, I did not want to experiment too much at the beginning. And maybe there was something about it which I didn´t like but I don´t remember it at the moment.

Those plant stem cell stuff may help with antioxidants and inflammation and maybe more but the data is rather thin so far. Many fishy companies around which try to use the word "stem cells" to make people buy ... look at this forum for example, the thread with the most views is the thread about a product which was so "clever" to put the word "stem" in its product name ...

https://www.lifelineskincare.com/blog/2 ... -skincare/

I like that quote XD
"One noted formulator says that many of the companies making plant stem cells claims are in fact, just taking cells from the “stem” of the leaf. Hence they call them “stem cells.” No, that’s not a joke. Neither is it funny. It’s an insult to the industry and consumers."

But I don´t want to exclude that we may use them too in the future. It depends. Currently we are fine and busy with our own stuff. Although the plant stem cells themselves can´t do the job which human stem cells do in the human body, the substances they produce may be beneficial. However, I don´t know for how long and if at all plant stem cells can stay alive in a cosmetic formulation full of preservation substances.
Last edited by SyntheseLabRat on Thu Dec 13, 2012 8:07 am, edited 1 time in total.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Thu Dec 13, 2012 3:56 am

tinytim wrote:fred and others have you heard of german product activogland which contains rhodanide as i got some from a german apo i have posted on general page but i will give you some info here as well http://www.rhodanide.com
Sorry, I have no opinion on rhodanide so far.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Thu Dec 13, 2012 6:50 pm

Since this is nearly the only forum where I am allowed to post, I will try to spread the information from here.

For all you Cetrizine lovers:

http://en.wikipedia.org/wiki/Cetirizine

Quote:
„Cetirizine ( /sɛˈtɪrɨziːn/), a second-generation[1] antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.”

The role of Histamine in hair growth is complicated. As with everything the action depends on the amount (concentration).
People who suffer from Lichen Planus and likely also people who suffer from alopecia areata have a problem with too much histamine in their scalp:

http://www.ncbi.nlm.nih.gov/pubmed/20868410
http://www.ncbi.nlm.nih.gov/pubmed/22211297

However, the concentrations used by some Cetrizine users for their topicals lead to about the same amount of Cetrizine on a small area of scalp which Lichen Planus sufferers take orally per day :shock:
It´s a riddle to me why people didn´t start with a low concentration to test this experimental approach for adverse effects before increasing the concentration.

But is a Histamine receptor antagonist really useful for androgenetic alopecia sufferers or is it maybe even detrimental for anagen induction?

http://www.ncbi.nlm.nih.gov/pubmed/9353643

Quote:
“Study on histamine related enzyme activities during murine hair cycle.
Abstract
The beginning of each anagen phase of the hair growth cycle appears to partially repeat the stages in the initial development of the hair cycle, but the regulatory mechanism of the hair cycle is unclear. We have investigated the levels of histamine related enzyme activities in the third hair cycle period of C3H mouse after depilation. The level of histidine decarboxylase activity increased just after depilation treatment and returned to the normal level within two weeks: this change was relevant to histamine content as we have previously reported. This result suggests that the histamine synthesising enzyme, histidine decarboxylase, activity may be involved in the distinctive process of hair re-growth, in particular, the initiation of the anagen phase.”

Without elaborating on them I give some additional links:

http://www.ncbi.nlm.nih.gov/pubmed/8840142
http://www.ncbi.nlm.nih.gov/pubmed/16116300
http://www.ncbi.nlm.nih.gov/pubmed/15808899
http://www.ncbi.nlm.nih.gov/pubmed/16183167

I doubt that nature has invented this protection mechanism for hair growth against chemo therapy agents … this protection mechanism likely plays a role also besides chemo therapy induced stress.

As I said, the situation is complicated. Histamine release may be needed during anagen induction. Although I am surprised that I have not heard much about this issue since that rather old publication. However, if some Histamine release is needed for anagen induction I personally would not try a selective H1 receptor inverse agonist.
I think the OC000459 approach is more promising, also the sucralfate and the valproic acid approach. But valproic acid may turn out to be dangerous with regard to tumor development in the future, although it seems to be more safe than LiCl; therefore I think one should wait for scientific long term data with LiCl. But if you can´t resist to try valproic acid, go for a low concentration.

Here is a link to some pictures of @babarbea who seems to have good results with OC000459:

http://club.doctissimo.fr/babarbea/5-mo ... 645302-jpg

For the valproic acid you may want to read my post on hairsite:

http://www.hairsite.com/hair-loss/board ... -DESC.html

But the concentration I mention there is the concentration used in the paper; you better start with a lower concentration, if at all. Better wait for long term data on the risky valproic acid.

Good luck!
Last edited by SyntheseLabRat on Fri Dec 14, 2012 4:20 am, edited 3 times in total.
You can contact me here advisor@functional-products.net .
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HRB 20588 Traunstein
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UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Jacob » Thu Dec 13, 2012 7:27 pm

Good info..please don't leave the forum 8)

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Re: Capillogain® Tonic

Post by Aks20 » Thu Dec 13, 2012 11:24 pm

Hi,

Per research reports, Minox can cause heart changes over sustained long term use, even at 2% over six months (increase in LV mass). Is the amount of Minox equivalent substance in your product similar? Are users likely to observe similar short term sides (racing heart, BP changes, dark circles etc) that are common with Minox?

Also, isnt Neogenic safer than VPA (apart from the expense). At least it is trialled and marketed by L'Oreal.

Lastly, can you guys make an 0C topical? We would all love a working topical as versus trying to mix chemicals in the toolshed.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Fri Dec 14, 2012 4:58 am

Aks20 wrote:Hi,

Per research reports, Minox can cause heart changes over sustained long term use, even at 2% over six months (increase in LV mass). Is the amount of Minox equivalent substance in your product similar? Are users likely to observe similar short term sides (racing heart, BP changes, dark circles etc) that are common with Minox?

Also, isnt Neogenic safer than VPA (apart from the expense). At least it is trialled and marketed by L'Oreal.

Lastly, can you guys make an 0C topical? We would all love a working topical as versus trying to mix chemicals in the toolshed.
The concentration of Triaminodil in Capillogain Tonic is below 2%. In addition the vehicle we use reduces systemic absorption compared to common solutions on the market.

I thought I made myself clear. I consider valproic acid (VPA) as not safe and I give the advice to wait for long term data in humans. The only reason I made that description on hairsite is that I know that many people won´t wait anyway and they won´t be able to resist and they will try VPA out anyway and if so I just want to give them the best help I can give in order to minimize casualties. But again, in my description on hairsite I translated the concentration of the article in numbers which you can use for your orientation, but it is more safe and more wise to start with a lower concentration with regard to the lacking long term data but it would be even more wise to not try VPA at all at the moment and wait for long term data.

I doubt that OC is allowed to be used in cosmetics. Kane with his "gangster" business may be able to sell you that stuff by saying "for research only" to all you "researchers" ;) but he may run into trouble with this sooner or later. But we are bound to the law and in Germany the restrictions are even harder, for example, we are not allowed to use ketoconazole in cosmetics which doesn´t seem to be a problem for other companies outside Germany. So I doubt we get the permission to use OC, however I am not absolutely sure so far, it is difficult to figure that out and costs some time.
You can contact me here advisor@functional-products.net .
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S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Fri Dec 14, 2012 11:02 am

We successfully produced the next batch of Capillogain Tonic yesterday. It will be available at amazon soon.
Capillogain Shampoo will be produced in the first week of January; the green tea extract is a little bit late which causes the delay.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Aks20 » Fri Dec 14, 2012 12:04 pm

Hi, actually I meant, why are people not trying Neogenic instead of VPA. All said and done, it did have human trials conducted by Dermatologists. Whereas VPA did not have any. http://www.loreal.com/_en/_ww/home/anim ... ss-kit.pdf

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Fri Dec 14, 2012 12:49 pm

@Aks20

But people do try Neogenic ... despite the fact that it is very expensive.

But why do you ask me why people try VPA and not Neogenic?
I don´t know that. I want to see clinical trials on VPA first, too, especially since it is a risky substance in principle.

Thank you for bringing that advertisement-file of Loreal to my attention. I will comment on it in my next post.
However, they don´t cite their clinical study. Can you give me a link to that study?
Last edited by SyntheseLabRat on Sat Dec 15, 2012 1:17 pm, edited 1 time in total.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Aks20 » Sat Dec 15, 2012 6:40 am

Thanks Synthese, look forward to your post. I am using it currently. But its all I have on Neogenic. Rest is more PR material. There are some studies on hairlosshelp and other forums mentioning that neogenic style substances work for hair loss. I can find those and post them for you.

I am one of those unfortunate people who are very susceptible to sides and hence stopped using Anti Androgens and Minox. On looking through your product list, I see it has a 5AR inhibitor - GLA - can this go systemic? Or is the medium designed to have it only be effective across the scalp?

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Sat Dec 15, 2012 1:58 pm

I think I won´t comment on that „scientific communication“, since I fear they may try to sue us and it´s not worth the hassle.
Just one note to other scientists who will know what I mean: They didn´t cite the authors of a Nature paper … XD


For Gamma-Linolenic Acid please read this publication:

http://www.ncbi.nlm.nih.gov/pubmed/9242500

Quote:
“The effect of gamma-linolenic acid is localized at the site of its application; topical application of gamma-linolenic acid did not affect the androgen-dependent growth of other organs such as testis, epididymis, seminal vesicle, and prostate. gamma-Linolenic acid, with low toxicity and absence of systemic effect, therefore may be potentially useful for treatment of androgen-dependent skin disorders.”
In addition, our vehicle is different than the one used in that publication and it should reduce the risk of systemic absorption even further. However, we can´t give you a guarantee that no systemic action will occur.
You can contact me here advisor@functional-products.net .
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https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Aks20 » Sat Dec 15, 2012 11:27 pm

Synthese you can send me a PM - then no legal issues.

These are the only public references I found to actual studies presented to professionals like you guys..
Apparently presented at the IHRS and not something I have access to.


17.00-17.20
The niche of human hair follicle stem cells: a specific environment
Bruno A. Bernard

SATELLITE SYMPOSIUM WITH LUNCH BOX by L’Oréal Recherche & Innovation
Beneficial effects of hypoxia
Chairpersons: Colin Jahoda/Bruno Bernard
12.15-12.35
Oxygen, a source of life and stress
C.Brahimi-Horn
12.35-12.55
Hypoxia and HIF pathway activity as factors of epidermal homeostasis
A. Panteleyev
12.55-13.15
Hypoxia and human hair follicle stem cells’ niche
B.A.Bernard/Dr.M.Rathman-Josserand

And they also submitted studies to the committee
HYPOXIA AND HUMAN HAIR FOLLICLE STEM/PROGENITOR CELLS. Michelle Rathman-Josserand
STEMOXYDINE® AND HAIR KENOGEN PHASE IN ANDROGENETIC ALOPECIA (AGA). Geneviève Loussouarn

http://www.ehrs2012.com/EHRS2012/Progra ... e%2019.pdf

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Re: Capillogain® Tonic

Post by Aks20 » Sat Dec 15, 2012 11:44 pm

Another interesting study that relates to LOreals claims

http://www.jci.org/articles/view/44478/pdf

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Re: Capillogain® Tonic

Post by tinytim » Sun Dec 16, 2012 3:26 am

hi synth and others about rhodanid i am going to use with capillogain as my hair and scalp is really the best ever im surprised no one has looked into this ingredient as it is for alopecia androgenica im not saying it will regrow any hair but its not too expesive and im going to keep using it,i have reduced to washing my hair to every other day and on non hair wash days apply two timesa day rhodanid really wetting whole scalp and hair and after washing hair using scalp roller and applying rhod while scalp pores are still open.

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Re: Capillogain® Tonic

Post by tinytim » Sun Dec 16, 2012 3:43 am

fred regarding gla what about neosil 101 and tb4 or 500 protosome inhibitor are these all the same as there is a guy injecting tb500 into his scalp on the other forum and also i heard that neosil regrew a nw7 hair back?

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Re: Capillogain® Tonic

Post by Aks20 » Sun Dec 16, 2012 4:28 am

Hi tiny, let us know how it works. I tried Activance - didnt do anything for me...but I could be wrong.

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Re: Capillogain® Tonic

Post by Aks20 » Sun Dec 16, 2012 4:53 am

Both Neosil and TBH have flopped judging by posts on hairlosshelp. OC is working though.

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Re: Capillogain® Tonic

Post by tinytim » Sun Dec 16, 2012 6:05 am

hi i think you need to use other regrowth products with rhod as it protects the hair and scalp from stuff like minox if you use it but the oc could be dangerous according to synth but there again is ru58841 as well as its not been trialed long enough in humans,is there a natural jacob protosome inhibitor?

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Sun Dec 16, 2012 8:19 am

Aks20 wrote:Another interesting study that relates to LOreals claims

http://www.jci.org/articles/view/44478/pdf
This one I already know. But thanks for the other info, I will take a look into it.
I don´t question the working mechanism but I don´t like the way they wrote their "scientific communication". But I prefer to not comment on it anymore, also not by PM.

I like the connection to STAT3.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058976/

STAT3 is important for hair growth.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC17660/
Last edited by SyntheseLabRat on Sun Dec 16, 2012 6:09 pm, edited 1 time in total.
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https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Sun Dec 16, 2012 8:25 am

tinytim wrote:hi i think you need to use other regrowth products with rhod as it protects the hair and scalp from stuff like minox if you use it but the oc could be dangerous according to synth but there again is ru58841 as well as its not been trialed long enough in humans,is there a natural jacob protosome inhibitor?
You balled things up. I said valproic acid (VPA) is risky to try before long term data is available.

However, in general every new substance is risky before long term data is available, but some are more risky than others. Valproic acid appears to be less risky then LiCl though but sill has the same WNT/beta-catenin mechanism which may promote tumor growth.
Last edited by SyntheseLabRat on Sun Dec 16, 2012 1:58 pm, edited 1 time in total.
You can contact me here advisor@functional-products.net .
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S.F.P. GmbH
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HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by oppenheimer82 » Sun Dec 16, 2012 12:10 pm

synthese lab rat, you need to incorporate cromolyn sodium into capillogain. i am using it now for 10 days straight and it totally stopped hair loss. you need about 4 grams for 100 ml. it's cheap and effective. works as good as oc000459. you are welcome my friend.

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Re: Capillogain® Tonic

Post by tinytim » Mon Dec 17, 2012 1:26 am

oppenheimer82 wrote:synthese lab rat, you need to incorporate cromolyn sodium into capillogain. i am using it now for 10 days straight and it totally stopped hair loss. you need about 4 grams for 100 ml. it's cheap and effective. works as good as oc000459. you are welcome my friend.
hi oppen is this safe to use cromolyn sodium also 10 days is not long enough for any trial but it may be interesting.

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Re: Capillogain® Tonic

Post by tinytim » Mon Dec 17, 2012 1:36 am

I want to say sorry to fred as the cappillogain subject has now gone into different products that are not even proven safe and i do hope that cap will give the regrowth i do want to ask fred though and i know jacob will not like it do you think we should start using minox with cap or use it on its own.
Also i do have some minox from uk clinic with medproxprogestorone have you heard of this as i did have some halt of loss on this.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Mon Dec 17, 2012 3:00 pm

@tinytim

You can use Capillogain Tonic on its own. But if you are used to another Minoxidil product and if you have good results with it you may want to keep it in your regimen. Just make sure you apply Capillogain Tonic first and there should be at least 10 minutes between the application of Capillogain Tonic and the other product.

I don´t know the product you mentioned. Please give me a link to a description of that product.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by Neutron » Tue Dec 18, 2012 1:20 am

SyntheseLabRat wrote:@tinytim

You can use Capillogain Tonic on its own. But if you are used to another Minoxidil product and if you have good results with it you may want to keep it in your regimen. Just make sure you apply Capillogain Tonic first and there should be at least 10 minutes between the application of Capillogain Tonic and the other product.

I don´t know the product you mentioned. Please give me a link to a description of that product.
Hi. I'm very keen to get off minox due to the side effects. As Capillogain contains the compound that works by a similar mechanism as minox (?), do you think it would be possible to make a swap and drop minox in favour of Capillogain without a huge shed? Thanks

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Re: Capillogain® Tonic

Post by tinytim » Tue Dec 18, 2012 1:24 am

SyntheseLabRat wrote:@tinytim

You can use Capillogain Tonic on its own. But if you are used to another Minoxidil product and if you have good results with it you may want to keep it in your regimen. Just make sure you apply Capillogain Tonic first and there should be at least 10 minutes between the application of Capillogain Tonic and the other product.

I don´t know the product you mentioned. Please give me a link to a description of that product.

Hi fred this is a link but its also available at many other tricho clinics in uk anyway i hope this link works http://www.belgraviacentre.com/minoxidil i wanted to add to anyone i do not buy anything from this clinic as they are quite pricey.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 18, 2012 1:36 pm

Neutron wrote: Hi. I'm very keen to get off minox due to the side effects. As Capillogain contains the compound that works by a similar mechanism as minox (?), do you think it would be possible to make a swap and drop minox in favour of Capillogain without a huge shed? Thanks

We cannot promise you that you won´t get a "shed" but I think the chances are very good that you will be very pleased when you swap.
You can contact me here advisor@functional-products.net .
-----------------------
S.F.P. GmbH
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Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 18, 2012 1:40 pm

tinytim wrote: Hi fred this is a link but its also available at many other tricho clinics in uk anyway i hope this link works http://www.belgraviacentre.com/minoxidil i wanted to add to anyone i do not buy anything from this clinic as they are quite pricey.
Thank you for the link. I prefer to not comment too much on other products.
However, if you think it works for you, you may want to keep it in your regimen if you have the money.
You can contact me here advisor@functional-products.net .
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S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 18, 2012 3:25 pm

One of our team is using Capillogain Tonic for about 3 to 4 months. He made some photos with a handheld microscope.
His new hairs are thin and very little pigmented (blonde) and they appear in the photos as thin white hairs, you will notice the difference from his terminal hairs. Some hairs start to get more pigmented. We think it is a pretty good start for the short time of application. The density of new hairs is pretty high. He says he had only about 10% of those vellus hairs before starting the applications; the density was never so high before and many of those new hairs got quite long already as you can see for yourself in the uploaded photos. He made photos from the front and the vertex. He is 47 years old and he does not use Finasteride or any other oral anti-hairloss drug and he doesn´t use any other topical besides our new Capillogain Shampoo prototype which he uses for about a month now.
Another member of our team also reports positive results, he is 66 years old. But I don´t know more about his results at the moment.
Have fun with the photos, I think they look pretty similar to those of @babarbea who uses OC in combination with Capillogain Tonic. Maybe that Shampoo with “coloration” effect which @israelite uses can help to make the thin and little pigmented hairs count earlier.
I think results will be even better for people who use in addition oral Finasteride and who are younger with a shorter hair loss history.

http://www.functional-products.net/index.php?id=113
http://www.functional-products.net/index.php?id=114
http://www.functional-products.net/index.php?id=115
http://www.functional-products.net/index.php?id=116
http://www.functional-products.net/index.php?id=117
http://www.functional-products.net/index.php?id=118

Don´t underestimate Capillogain Tonic just because it is rather inexpensive ;)
Last edited by SyntheseLabRat on Tue Dec 18, 2012 5:34 pm, edited 1 time in total.
You can contact me here advisor@functional-products.net .
-----------------------
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Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by oppenheimer82 » Tue Dec 18, 2012 4:21 pm

SyntheseLabRat wrote:One of our team is using Capillogain Tonic for about 3 to 4 months. He made some photos with a handheld microscope.
His new hairs are thin and very little pigmented (blonde) and they appear in the photos as thin white hairs, you will notice the difference from his terminal hairs. Some hairs start to get more pigmented. We think it is a pretty good start for the short time of application. The density of new hairs is pretty high. He says he had only about 10% of these vellus hairs before starting the applications, the density was never so high and many of those new hairs got quite long already as you can see for yourself in the uploaded photos. He made photos from the front and the vertex. He is 47 years old and he does not use Finasteride or any other oral anti-hairloss drug and he doesn´t use any other topical ´besides our new Capillogain Shampoo prototype which he uses for about a month now.
Another member of our team also reports positive results, he is 66 years old. But I don´t know more about his results at the moment.
Have fun with the photos, I think they look pretty similar to those of @babarbea who uses OC in combination with Capillogain Tonic. Maybe that Shampoo with “coloration” effect which @israelite uses can help to make the thin and little pigmented hairs count earlier.
I think results will be even better for people who use in addition oral Finasteride and who are younger with a shorter hair loss history.

http://www.functional-products.net/index.php?id=113
http://www.functional-products.net/index.php?id=114
http://www.functional-products.net/index.php?id=115
http://www.functional-products.net/index.php?id=116
http://www.functional-products.net/index.php?id=117
http://www.functional-products.net/index.php?id=118

Don´t underestimate Capillogain Tonic just because it is rather inexpensive ;)
very very nice indeed. i see hundreds of new vellus hairs. but you need to reformulate this product and add in a powerful GPR44 blocker. then your product will become supreme.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 18, 2012 5:47 pm

oppenheimer82 wrote: very very nice indeed. i see hundreds of new vellus hairs. but you need to reformulate this product and add in a powerful GPR44 blocker. then your product will become supreme.
The ideas are not the problem, the regulations are. You can´t just toss in a cosmetic product whatever comes to your mind. Especially in Germany the regulations are hard. It is very difficult to create a product in Germany which is of any use at all. Well despite Capillogain Tonic of course ;)
But thanks for the hint, it is appreciated nonetheless.
Maybe we can incorporate stuff like that when we relocate to Cambodia or Costa Rica ;)

Btw, sorry for the delayed resupply at amazon (US); somebody in the US sent our batch back to Germany XD
But we already sent another batch to amazon, it should arrive soon.
You can contact me here advisor@functional-products.net .
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HRB 20588 Traunstein
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UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by israelite » Tue Dec 18, 2012 7:27 pm

good ingredinets in a good vehicle give good results!

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Tue Dec 18, 2012 9:27 pm

Just to remind you:
1) Capillogain Tonic is not hiding behinde the Minox-Effect. There is only little Triaminodil in Capillogain Tonic which is why nobody has reported about Minox-typical sides with Capillogain Tonic so far (and because of the smart vehicle).

2) Capillogain Tonic contains no allergy promoting Propylene Glycol (PG) and it has a lower Ethanol content than many other products on the market.

3) Capillogain Tonic absorbs fast and without noticeable residue on the skin.


Since Capillogain Tonic contains only little Minox, one may think of the possibility that good Minoxidl-responders may profit from a combined use of Capillogain Tonic and a Minoxdil product since the working mechanisms are at least in part different.
Our team member, who made the above photos, says he is a Minox-nonresponder. However, Capillogain Tonic seems to work for him. There are different explanations possible:
1) Wrong application of Minoxidil and therefore no results in the past.
2) His former Minoxidil product had an insufficient vehicle. Whereas the Triaminodil in Capillogain Tonic, although dosed low, benefits from an effective vehicle. In this case the user may not be a Minox-nonresponder but the vehicle of his former Minoxidil product was not effective enough for his cause.
3) The other active agents in Capillogain Tonic (others than Triaminodil), caused the results fort he user which are visible in the above posted photos.
You can contact me here advisor@functional-products.net .
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http://www.functional-products.net/en/p ... ss-shampoo.

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Re: Capillogain® Tonic

Post by tinytim » Wed Dec 19, 2012 2:08 am

hi fred many thanks i received my cap this morning wed 12th dec i see you say you are going to relocate will that make uk del longer? and also the pics are good did he use it the once a day or twice i see on the bottle it says once and also only three pipettes full.








.

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Re: Capillogain® Tonic

Post by SyntheseLabRat » Wed Dec 19, 2012 3:05 am

tinytim wrote:hi fred many thanks i received my cap this morning wed 12th dec i see you say you are going to relocate will that make uk del longer? and also the pics are good did he use it the once a day or twice i see on the bottle it says once and also only three pipettes full.

OMG, nooo, we are not relocating, I was just kidding *lol* XD

Good question tim, I forgot to mention that he used it most of the time 2 times a day. We will change that on the Capillogain bottle from one to twice per day.

Capillogain Tonic is available at amazon again. The parcel somehow found its way to amazon and did not come back to Germany.
Last edited by SyntheseLabRat on Wed Dec 19, 2012 4:03 am, edited 2 times in total.
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-----------------------
S.F.P. GmbH
Bahnhofstr. 72
D-84558 Kirchweidach
Germany

HRB 20588 Traunstein
St.Nr. 141/137/40338
UID DE275313171
https://www.functional-products.net/pro ... tonic.html
http://www.functional-products.net/en/p ... tonic.html
http://www.amazon.com/Capillogain%C2%AE ... apillogain
http://www.functional-products.net/en/p ... ss-shampoo.

Fizzball
Prolific Poster
Posts: 204
Joined: Sat May 16, 2009 11:22 am
Hair Loss Type: Don't Know
Have you had a hair transplant?: No

Re: Capillogain® Tonic

Post by Fizzball » Wed Dec 19, 2012 3:15 am

I would love to trial this product but I am committed to another product at the moment and am giving that a fair trial period. If nothing else becomes available by the time I finish my trial period and this product produces terminal hair I will be more than happy to give it a fair go.
There are a lot of products available that create vellus hairs, however out of all such products no one at all has come out and represented their products as SyntheseLabRat has and also has displayed a great deal of knowledge, dedication and dare I even say it... integrity.

I hope to see more images and feedback from people soon.
Don't mistake my optimism for stupidity

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