Capillogain® Tonic

[tinytim]

hi fred many thanks i received my cap this morning wed 12th dec i see you say you are going to relocate will that make uk del longer? and also the pics are good did he use it the once a day or twice i see on the bottle it says once and also only three pipettes full.

OMG, nooo, we are not relocating, I was just kidding *lol* XD

Good question tim, I forgot to mention that he used it most of the time 2 times a day. We will change that on the Capillogain bottle from one to twice per day.

Capillogain Tonic is available at amazon again. They parcel somehow found its way to amazon and did not come back to Germany.

thanks fred hahaha i glad you are staying here and in germany applied my first dose after washing hair and it goes on great i did shake the bottle then thought i should have only tipped up and down will it hurt to shake every time? i will apply next dose tonight.
By the way fred i have seen cap on hairlosshelp and hairsite and it does not say you are banned,unless its immortal or omgs site which i would not think they would do that.

[helpneed]

Am a newbie so be patient please.

I read that Minoxidil is kind of like a perpetual 'monkey on your back', meaning if you discontinue, you will get shedding / follicles falling out.

Since Capillogain does not contain Minoxidil (am I right?), can I safely stop using it if I later decided so?

Sorry for the noob question!

[Flynn]

Hi Synth,

Have you researched Threonate? Honestly, I think adding this to the mix could do more for your sales than any other ingredient you're considering. You've featured numerous agents with connections to various factors thought to affect hair growth... Why not add something that's closer to WNT than anything else we've found yet?

http://www.nature.com/jid/journal/v128/ ... 0999a.html

"A co-culture system using outer root sheath (ORS) keratinocytes and DP cells showed that DHT inhibits the growth of ORS cells, and neutralizing antibody against DKK-1 significantly reversed the growth inhibition of ORS cells."

http://www.bmbreports.org/jbmb/pdf.php? ... UyOS5wZGY=

"We observed via RT-PCR analysis and enzyme-linked immunosorbent assay that DHT-induced DKK-1 expression was attenuated in the presence of L-threonate. We also found that
DHT-induced activation of DKK-1 promoter activity was significantly repressed by L-threonate. Moreover, a co-culture system featuring outer root sheath (ORS) keratinocytes and DPCs
showed that DHT inhibited the growth of ORS cells, which was then significantly reversed by L-threonate. Collectively, these results indicate that L-threonate inhibited DKK-1 expression in DPCs and therefore is a good treatment for the prevention of androgen-driven balding."

http://www.touchbriefings.com/pdf/3196/walker.pdf

"Dickkopf family members (Dkk1 and Dkk2) and secreted frizzled related proteins (Sfrps) are families of extracellular proteins that negatively modulate canonical Wnt signalling."

http://www.ncbi.nlm.nih.gov/pubmed/23190887

"A signal first arising in the dermis to initiate the development of hair follicles has been described for many decades. Wnt is the earliest signal known to be intimately involved in hair follicle induction."

http://www.sciencedirect.com/science/ar ... 8206004078

"More widespread Dkk1 expression (driven by the Col1A1 3.6 kb promoter) yielded osteopenia with forelimb deformities and hairlessness,"

Some salt studies:
http://www.ncbi.nlm.nih.gov/pubmed/21986570
"Calcium L-threonate was well tolerated in healthy Chinese subjects, with no pattern of dose-related adverse events. Plasma exposure increased with dose escalation, but linear pharmacokinetics were not observed over the studied doses. L-threonate was absorbed rapidly, and its absorption was enhanced by food intake. No systemic accumulation appeared after repeated administrations."
http://www.ncbi.nlm.nih.gov/pubmed/16554191
http://www.ncbi.nlm.nih.gov/pubmed/23229796
http://www.ncbi.nlm.nih.gov/pubmed/18971870
http://www.ncbi.nlm.nih.gov/pubmed/20152124

I don't know if this is too relevant, but it's study of topical formulations of ASC-2P, another metabolite of Vitamin C.

http://www.springerlink.com/content/v08502h52x1132l1/

"Furthermore, the use of PMX of A2P with empty cationic MLV demonstrated minimal or no metabolism of the parent drug, indicating that A2P might be better benefited with the use of PMX rather than entrapment into the MLVs."

I also want to sound off on selling your vehicle separately. The interest in it would be almost incalculably high.

Cheers,
Flynn.

[oppenheimer82]

Just to remind you:
1) Capillogain Tonic is not hiding behinde the Minox-Effect. There is only little Triaminodil in Capillogain Tonic which is why nobody has reported about Minox-typical sides with Capillogain Tonic so far (and because of the smart vehicle).

2) Capillogain Tonic contains no allergy promoting Propylene Glycol (PG) and it has a lower Ethanol content than many other products on the market.

3) Capillogain Tonic absorbs fast and without noticeable residue on the skin.


Since Capillogain Tonic contains only little Minox, one may think of the possibility that good Minoxidl-responders may profit from a combined use of Capillogain Tonic and a Minoxdil product since the working mechanisms are at least in part different.
Our team member, who made the above photos, says he is a Minox-nonresponder. However, Capillogain Tonic seems to work for him. There are different explanations possible:
1) Wrong application of Minoxidil and therefore no results in the past.
2) His former Minoxidil product had an insufficient vehicle. Whereas the Triaminodil in Capillogain Tonic, although dosed low, benefits from an effective vehicle. In this case the user may not be a Minox-nonresponder but the vehicle of his former Minoxidil product was not effective enough for his cause.
3) The other active agents in Capillogain Tonic (others than Triaminodil), caused the results fort he user which are visible in the above posted photos.

it's the vehicle for sure. to this day i still can not comprehend why the makers of rogaine did not invent an amazing carrier vehicle for their minoxidil solution to enhance absorption and to make the minoxidil to get into the hair shaft in an instance. it really baffles me. your product looks great, only not enough ingredients to tackle pgd2 formation. this discovery by dr cotsarelis is crucial for hair loss sufferers. please add in something legal to the target and block the gpr44 receptor. i went to the german forum, as i am fluent in german and you are also very helpful on that board. lot's of sceptive germans though, it's in their nature i guess.

[israelite]

what can i add to my capillogain

[Flynn]

this discovery by dr cotsarelis is crucial for hair loss sufferers. please add in something legal to the target and block the gpr44 receptor.

Is this reality? The first response after my post, which identifies the critical import of WNT, would feature a plea to target gpr44, which is almost obscenely far from WNT.

http://www.youtube.com/watch?v=BNsrK6P9QvI

The love for Cotsie's work is very nauseating to anyone who surveys the current research trends. Dermatology researchers are excited about WNT and virtually ignore Cotsie's stuff.

[SyntheseLabRat]

@Flynn

L-Threonate will be in one of our Shampoos.
Actually I was the first who mentioned Asc-2P to the hair growth related boards in 2005. I visited the EHRS 2005 in Zurich and there was a poster session and one poster was about Asc-2P. Several publications on Asc-2P since then and the same authors made the L-Threonate paper recently. I use Asc-2P as an oral supplement for years.

I am a bit busy at the moment, but I will try to comment on the posts here later.

[SyntheseLabRat]

I pointed out several years ago on hairsite (you can´t find those posts anymore since they are in old folders, at least I guess they are hard to find) the importance of mast cell degranulation, I elaborated much on it, it is the same avenue as this PGD2 approach. However, the histamine issue is difficult/two sided; histamine may be important for anagen induction therefore you have to be careful how you approach the PGD2 issue. The receptor blocking approach may be better. I like the omega 3 fatty acid apporach, eico... and doco... are even 5AR inhibitors, well at least one of them I think, have to look it up again. But Gamma-Linolenic acid rocks, too. I didn´t want to go for eico... and doco... because I did not want to use stuff that has not been shown to be safe and effective in publications because we don´t want to use our customers as lab rats.

Well, we have something against the PGD2 issue in Capillogain Tonic. You just have to follow the links on our page which we give for each active agent. Sophora Flavescens Extract and gamma-Linolenic acid do their part.

[SyntheseLabRat]

I would love to trial this product but I am committed to another product at the moment and am giving that a fair trial period. If nothing else becomes available by the time I finish my trial period and this product produces terminal hair I will be more than happy to give it a fair go.
There are a lot of products available that create vellus hairs, however out of all such products no one at all has come out and represented their products as SyntheseLabRat has and also has displayed a great deal of knowledge, dedication and dare I even say it... integrity.

I hope to see more images and feedback from people soon.

Thank you for your kind words.
Yes, vellus hair can be achieved also with other products. But let´s see how things develop, he used Capillogain Tonic only for 3 to 4 months and some of his new hairs are quite long, let´s see how how the second cycle looks like. Some users report also about thickening of weakened hairs with Capillogain Tonic. But if those hairs get stronger and in addition on bald areas vellus hair appears it is going into the right direction I think.
But this is just the beginning. The major improvements to our products are still to come.
One small step will be the addition of a FGF-5 inhibitor soon that may help those vellus hairs.
I am a resourceful LabRat, I still hold some aces

[SyntheseLabRat]

thanks fred hahaha i glad you are staying here and in germany applied my first dose after washing hair and it goes on great i did shake the bottle then thought i should have only tipped up and down will it hurt to shake every time? i will apply next dose tonight.
By the way fred i have seen cap on hairlosshelp and hairsite and it does not say you are banned,unless its immortal or omgs site which i would not think they would do that.

Don´t shake vigorously. Just tilt it a few times. I know that fragile growth factors like KGF get destroyed by strong shaking. Since Capillogain contains agents like Procyanidin B3, which may have a somewhat fragile susceptible structure too, it is more safe to just tilt the bottle a few times instead of shaking it like mad

I am allowed to post on hairsite but hairsite has very little activity.
I am allowed to post here and on a German board. I think I tried to register on HLH but got banned ... for ever XD or they just deleted my post related to Capillogain, I don´t remember, maybe I ball some boards up.

[SyntheseLabRat]

Am a newbie so be patient please.

I read that Minoxidil is kind of like a perpetual 'monkey on your back', meaning if you discontinue, you will get shedding / follicles falling out.

Since Capillogain does not contain Minoxidil (am I right?), can I safely stop using it if I later decided so?

Sorry for the noob question!

Capillogain Tonic contains a low amount of Triaminodil, which has a similar chemical structure to Minoxidil.
So far, we have no data on what happens if you stop Capillogain Tonic, sorry.

[helpneed]

Am a newbie so be patient please.

I read that Minoxidil is kind of like a perpetual 'monkey on your back', meaning if you discontinue, you will get shedding / follicles falling out.

Since Capillogain does not contain Minoxidil (am I right?), can I safely stop using it if I later decided so?

Sorry for the noob question!

Capillogain Tonic contains a low amount of Triaminodil, which has a similar chemical structure to Minoxidil.
So far, we have no data on what happens if you stop Capillogain Tonic, sorry.

Fair enough. Don't expect you to have data since Capillogain Tonic is a new product.

But might something like shedding occur, purely theoretically speaking? Sorry for being pushy. Am tempted to try your product; just don't want to regret later on (and not able to discontinue).

Thanks!

[SyntheseLabRat]

Am a newbie so be patient please.

I read that Minoxidil is kind of like a perpetual 'monkey on your back', meaning if you discontinue, you will get shedding / follicles falling out.

Since Capillogain does not contain Minoxidil (am I right?), can I safely stop using it if I later decided so?

Sorry for the noob question!

Capillogain Tonic contains a low amount of Triaminodil, which has a similar chemical structure to Minoxidil.
So far, we have no data on what happens if you stop Capillogain Tonic, sorry.

Fair enough. Don't expect you to have data since Capillogain Tonic is a new product.

But might something like shedding occur, purely theoretically speaking? Sorry for being pushy. Am tempted to try your product; just don't want to regret later on (and not able to discontinue).

Thanks!

What do you really mean by "shedding" on stopping a product? There is no cure so far and if you stop a product that worked for you of course you will see consequences.
I guess you are afraid to end up with less hair after stopping than the placebo group, right?
Theoretically that can´t be excluded completely but I think it is very unlikely.

[helpneed]

What do you really mean by "shedding" on stopping a product? There is no cure so far and if you stop a product that worked for you of course you will see consequences.
I guess you are afraid to loose end up with less hair after stopping than the placebo group, right?
Theoretically that can´t be excluded completely but I think it is very unlikely.

[/quote][/quote]

Was referring to the Price et al.'s (1999) study on minoxidill.

Not sure if it is a faithful summary of the findings, but below summaries what I was trying to say:
"Price et al did an OUTSTANDING topical minoxidil study in 1999 which answered a lot of important questions about its use. Their test-subjects applied it in the usual fashion for a full 96 weeks, and hair counts and weights were carefully measured every six weeks throughout the trial. After 96 weeks, the topical minoxidil was discontinued in all subjects, while counts and weights were continued. On the first measurement afterwards (six weeks), a drop in counts and weights was observable, and they were much more significant on the second measurement afterwards (12 weeks). Counts had "bottomed-out" at that point, and even rose slightly on the third count after that (18 weeks), although weights still declined slightly on the third count. By the fourth count afterwards (24 weeks), counts and weights were pretty much nearly back to normal (close to what the placebo users had, in other words)."
(SOURCE: http://www.hairlosshelp.com/forums/mess ... adid=95445)

[SyntheseLabRat]

Yes, I thought you were referring to that study.

http://www.ncbi.nlm.nih.gov/pubmed/10534633

But I already gave you my answer.
When consumer numbers increase we may come up with a version without Triaminodil if enough people want it.

[Flynn]

@Flynn

L-Threonate will be in one of our Shampoos.
Actually I was the first who mentioned Asc-2P to the hair growth related boards in 2005. I visited the EHRS 2005 in Zurich and there was a poster session and one poster was about Asc-2P. Several publications on Asc-2P since then and the same authors made the L-Threonate paper recently. I use Asc-2P as an oral supplement for years.

I am a bit busy at the moment, but I will try to comment on the posts here later.

Great news! When do you think the shampoo might come out? I notice the first is still yet to hit market.

I thought ASC-2P was mostly metabolized by the liver and allowed little to linger in serum? Is that not the case?

Can I ask your plans on the anti-dandruff ingredients? Some of us aren't too keen on the anti-androgens and would hope ketoconazole doesn't make it in the mix.

[SyntheseLabRat]

I have all the Proforma Invoices collected for the active agents we need, some are already paid and the items are on their way to our location. But we first will produce Capillogain Shampoo in the first week of January before we proceed with the second Shampoo. I guess the second Shampoo will be available at the end of January.

We use piroctone olamine.
Here you can read why:

http://www.ncbi.nlm.nih.gov/pubmed/18498517

Most companies don´t like it because it is expensive. But it is the best anti-dandruff agent. I like ketoconazole too but we are not allowed to use it in Germany for cosmetic products.

I already use the prototype of that second Shampoo. I think it has an anti-itch effect.

[tinytim]

Re rogaine or regaine as called in uk is it the propglycol that is the carrier vehicle which as many of us know is way too greasy and irritates some of our scalps is that why some that use liposommes like spectral with minox sulphate may be better,but capillogain if the triaminodil works i do not see why they would need to add a product without it.
By the way synth fred i am using a scalp roller with the cap i also have a box of neogenic but really do not want to use it as i will not know whats working any thoughts on that? i am using a natural anti dht and also L Lysine 1000mg a day as there were studies that the latter made finasteride work better but as said i have dropped finas and gone onto natural instead,the info was on hairlossresearch web site.

[tinytim]

forgot to add the red bottle of alpecin has olimine in it fred but would the caffeine in it ruin the cap lotion?

[SyntheseLabRat]

forgot to add the red bottle of alpecin has olimine in it fred but would the caffeine in it ruin the cap lotion?

What do you mean? You want to toss in some Caffeine into Capillogain or are you talking about washing your hair with a caffeine Shampoo after using Capillogian Tonic?

[SyntheseLabRat]

Re rogaine or regaine as called in uk is it the propglycol that is the carrier vehicle which as many of us know is way too greasy and irritates some of our scalps is that why some that use liposommes like spectral with minox sulphate may be better,but capillogain if the triaminodil works i do not see why they would need to add a product without it.
By the way synth fred i am using a scalp roller with the cap i also have a box of neogenic but really do not want to use it as i will not know whats working any thoughts on that? i am using a natural anti dht and also L Lysine 1000mg a day as there were studies that the latter made finasteride work better but as said i have dropped finas and gone onto natural instead,the info was on hairlossresearch web site.

You don´t need a scalp roller for Capillogain Tonic since it absorbs very well. Dermal rollers not only cause the so-called "wounding-effect" which is said to help hair growth, dermal rollers also increase collagen production which is why they are used for the facial skin, too. But increase of collagen production in the scalp may lead to fibrosis which is bad for hair growth. In addition dermal rollers mayy increase inflammation. You don´t need a dermal roller for Capillogain Tonic.

I think you should use both now since you already bought both, but when you run out of Neogenic you continue only with Capillogain Tonic and in case your results decrease you may switch to Neogenic or add it agian.

[tinytim]

many thanks fred for the answers i ment with alpecin someone at another forum said caffein may hinder minoxidil so i wonder if it may with cap anyway i will use the new shampoo when its available im using a sulphate free teatree shampoo at this time.
I see you have gla in cap i nealy was going to try to get some to apply as well? im still not sure whether to use the neogenic as yet because it would have to be applied first after hair wash as using 6mls a day would wash the capilogain off the scalp if it was used after would it not?
I am not sure if proscar has ever done anything for my hair as i have it for prostate problems but have now stopped taking and using foligain which is a natural anti dht i even tried dutasteride for over a year at 0.5mg a day which also did nothing in fact i increased the dose to the optimium for hair regrowth that were in the trials 2.5mgs a day and again did nothing so it shows i wonder is dht the thing in mpb.

[Jacob]

You don´t need a scalp roller for Capillogain Tonic since it absorbs very well. Dermal rollers not only cause the so-called "wounding-effect" which is said to help hair growth, dermal rollers also increase collagen production which is why they are used for the facial skin, too. But increase of collagen production in the scalp may lead to fibrosis which is bad for hair growth. In addition dermal rollers mayy increase inflammation. You don´t need a dermal roller for Capillogain Tonic.

Speaking of fibrosis..I've used Elsom's anti-fibrosis product for some time. Did I read right that you were saying Raspberry Ketone is supposed to help in this area?

On the dermarollers..I took a break from mine for some time after purchasing that Hair Sonic scalp massager. Have been using the roller off and on lately though. And no..I haven't used either one when using Capillogain.

[SyntheseLabRat]

You don´t need a scalp roller for Capillogain Tonic since it absorbs very well. Dermal rollers not only cause the so-called "wounding-effect" which is said to help hair growth, dermal rollers also increase collagen production which is why they are used for the facial skin, too. But increase of collagen production in the scalp may lead to fibrosis which is bad for hair growth. In addition dermal rollers mayy increase inflammation. You don´t need a dermal roller for Capillogain Tonic.

Speaking of fibrosis..I've used Elsom's anti-fibrosis product for some time. Did I read right that you were saying Raspberry Ketone is supposed to help in this area?

On the dermarollers..I took a break from mine for some time after purchasing that Hair Sonic scalp massager. Have been using the roller off and on lately though. And no..I haven't used either one when using Capillogain.

I didn´t say Raspberry Ketone helps against skin fibrosis, and you know that.
Raspberry Ketone increases dermal IGF-1 which in turn increases collagen production which is beneficial for facial skin. However, IGF-1 is also beneficial for hair growth and the human in vivo experiment has shown that the benefit is greater than eventual negative effects:

http://www.ncbi.nlm.nih.gov/pubmed/18321745

However, oral Rasperry Ketone seems to have an antifibrotic effect by increasing adiponectin:

http://www.todaysdietitian.com/newarchi ... 2p80.shtml

Quote:
"Proponents of RK as a weight-loss aid base their claims on the compound’s ability to increase circulating levels of adiponectin, a hormone secreted from adipose tissue that plays a key role in carbohydrate and fat oxidation that also may exert anti-inflammatory, antifibrotic, and antiatherogenic effects."

[SyntheseLabRat]

many thanks fred for the answers i ment with alpecin someone at another forum said caffein may hinder minoxidil so i wonder if it may with cap anyway i will use the new shampoo when its available im using a sulphate free teatree shampoo at this time.
I see you have gla in cap i nealy was going to try to get some to apply as well? im still not sure whether to use the neogenic as yet because it would have to be applied first after hair wash as using 6mls a day would wash the capilogain off the scalp if it was used after would it not?
I am not sure if proscar has ever done anything for my hair as i have it for prostate problems but have now stopped taking and using foligain which is a natural anti dht i even tried dutasteride for over a year at 0.5mg a day which also did nothing in fact i increased the dose to the optimium for hair regrowth that were in the trials 2.5mgs a day and again did nothing so it shows i wonder is dht the thing in mpb.

Yes, I would like to see an experiment where one group uses plain Minoxidil and another uses Minoxidil plus some product with caffeine; it would be interesting to see if the caffeine decreases the action of Minoxidil. Caffeine is an adenosine receptor inhibitor.

http://www.ncbi.nlm.nih.gov/pubmed/11886528

According to this publication Minoxidil works mainly be releasing adenosine to the extracellular space and this adenosine in turn activates the adenosine receptors from the outside which in turn leads to an increase of VEGF. However, I have my doubts. This may be part of the action of Minoxidil but maybe not the main mechanism since it appears that pure adenosine does not work better than Minoxidil. However, even if this adenosine-mechanism of Minoxidil is only part of its action, application of Caffeine may reduce the effectiveness of Minoxidil. But since the above by me mentioned experiment has not been conducted yet we can´t be sure. But since many people use Minoxidil as their major weapon in their fight against hair loss we did not want to risk anything which is one reason (besides others) why we did not include caffeine in any of our products so far. However, as I described in one of my posts before, I am also not completely convinced of adenosine. Future will tell if we use one or the other in the future after more data got available.
However, tossing adenosine and caffeine in the same product is really a stupid idea but I bet you will find companies who do that XD
Caffeine is also very difficult to dose. It works only in a narrow concentration window. Too much hurts, the reason may be the inhibition of the adenosine receptors. If I remember right even a too low concentration of caffeine had a negative effect which makes it really hard to dose, especially if you use a different vehicle than was used in the studies. That is another reason why we stay away from caffeine for the moment; it is not worth the risk, we have enough other better options.

Capillogain Tonic contains Triaminodil which has a similar spectrum of action as Minoxidil. If your caffeine product has not worked very well so far you may try without it for a while.

If you wait at least 10 minutes after the application of Capillogain you can apply whatever you want. Capillogain absorbs so fast that you won´t wash it off.

[Jacob]

Fred..you need to chill a bit. I noticed you go off a bit on ppl for the littlest things.

I found what I was referring to: "The increase in IGF-1 will boost collagen production which is a good thing for facial skin. Increase collagen production may become a problem on the scalp for hair growth if fibrosis sets in. However, the study on Raspberry Ketone clearly showed the positive effect of Raspberry Ketone on hair growth for the used concentration."

I just recall the Rasberry Ketone in the discussion. Notice I was asking if that's what I had read.

[Jacob]

Maybe it's just a language...reading things differently....sort of...thingy....

[tinytim]

by the way happy christmas and new year although i will still be around on forum unless they close that is hahaha. I forgot to add alopecia uk i have mentioned capilogain but have they do not post very often on that web site.

[SyntheseLabRat]

Maybe it's just a language...reading things differently....sort of...thingy....

I am sorry if I did sound angry. I am not angry, I am fine. I am very busy but still I try to answer questions late in the night, that may go to the expense of hitting the right tone each and every time and it really may be a language problem too since I may not be aware of what has a provocative meaning/undertone and what hasn´t. I just know that I have not said something like that and I thought you should know it too. I may should have put a smiley ";)" behind it or better not written it at all.
Sorry again, no offence meant. Blame it on my bad English skills, I was always a science kid, not interested in languages at all. Well, looking back that was a mistake, English is very important for scientists.

[SyntheseLabRat]

Happy Christmas time!

[Jacob]

Everything is ok...just wanted to make sure people weren't pulling their hairs out here

I was going to start a new thread on this...but I guess I'll just say it here- Merry Christmas!...Happy New Year!- I'll be back after the 1st! (Sam..if you're reading this..you really need to get more mods on here. Please.)

[tinytim]

hi synth fred i am wondering if you apply twice a day do you have to apply three pipettes full as it says on the bottle three for once a day? or as in minoxidil case 1ml twice a day?

[SyntheseLabRat]

hi synth fred i am wondering if you apply twice a day do you have to apply three pipettes full as it says on the bottle three for once a day? or as in minoxidil case 1ml twice a day?

The amount per application depends on the area you want to apply it to:

only frontal area: 1mL
frontal + middle part: 2mL
frontal + middle part + vertex: 3mL

One application per day, as mentioned on the bottle, works. But some people used it twice a day despite the note on the bottle and it worked for them, too. However, we don´t know if one application per day wouldn´t have worked the same for them.
If you want to push it and if you can handle the second application in your daily regimen, you may want to try a two times per day application routine. However, if you don´t notice better results with the two times application you may want to get back to the once per day application routine.

[israelite]

I notice my capillogain will last me a couple months. here is an updated progress phtot

[SyntheseLabRat]

Compared with your earlier photos on page 2, I have the impression those tiny hairs got longer, right?

[israelite]

Compared with your earlier photos on page 2, I have the impression those tiny hairs got longer, right?

yes!. here is phtos comparing the 2.

[SyntheseLabRat]

Here is a new photo of my colleague. I think it is from his vertex region. It may not be of good quality but I thought it might be interesting nevertheless. I guess it is difficult to take a photo in a region where still is some terminal hair present.

http://www.functional-products.net/index.php?id=119

If you take a closer look you can see many less pigmented hairs of about the same size. They are not that small anymore and they start to have cosmetic impact.

[justwannagetoverhair]

Hi SyntheseLabRat, I have suffered from diffuse thinning my entire scalp not sure why in less than a year (coincidentally it started when I had started gym and protein shakes). Saw this thread and thought of giving this a try, my question is
1) will there be any kind of initial shedding like minoxidil, what should I be expecting? (they always say you need to shed first only to give way to new strong hairs, but that can also mean the treatment is not working either!)
2) thinking of using it daily right after night shower on dry scalp and leave it
3) will there be any issue with this treatment as I live in asian climate/environment
4) is this alone sufficient? currently not on any other treatment at all (no fin,minox or anything like that) only some soy and green tea and health supplements.

Thanks a bunch...Merry Christmas

[SyntheseLabRat]

@justwannagetoverhair

1) So far nobody has reported an initial shed with Capillogain Tonic.

2) Your plan is ok if you can stand the "funky" smell at night which may still be present in the morning. If you shower also in the morning it won´t be a problem. But if you don´t shower in the morning, you may want to apply it about half an hour or longer before your night shower. Capillogain Tonic absorbs very fast.

3) I can´t think of any problem due to asian climate. However, store the bottles in a cool and dry place. You can store the bottles also in the fridge (5 to 8 degree Celsius), but don´t freeze it.

4) I posted some links to photos of my colleague here. He uses only Capillogain Tonic, nothing else, no Fin and no Dut. But I think the results will be better in combination with Fin or Dut or other additional products.

[tinytim]

Compared with your earlier photos on page 2, I have the impression those tiny hairs got longer, right?

yes!. here is phtos comparing the 2.

Hi israelite how long have you been using capillogain and is it that thats causing the regrowth or are you on other topicals and oral products?

[Flynn]

Hi Synth,

Do you think your shampoo will be able to effectively deliver the Threonate to the follicles? Could there be metabolism or absorption issues?

Also, do you have an idea of what concentration you'll use?

Thanks again for all your time.

[israelite]

Compared with your earlier photos on page 2, I have the impression those tiny hairs got longer, right?

yes!. here is phtos comparing the 2.

Hi israelite how long have you been using capillogain and is it that thats causing the regrowth or are you on other topicals and oral products?

i been using capillogain for will over a month now! i always had very small hairs but now they are growing. recently i have only been applying 4 topicals! capillogain, ru, vpa, and minox sulfate.

[SyntheseLabRat]

Hi Synth,

Do you think your shampoo will be able to effectively deliver the Threonate to the follicles? Could there be metabolism or absorption issues?

Also, do you have an idea of what concentration you'll use?

Thanks again for all your time.

Here you can take a look at a microscope photo of our special microencapsulating vehicle for Capillogain Shampoo:

http://www.functional-products.net/index.php?id=110

It was not easy to find a way to make that technology work in a Shampoo.

However, Asc-2P did not work with this vehicle if I remember right. I don´t know if L-Threonate will work, since it has not arrived yet; I fear it has not even been paid by us yet.
The second Shampoo, which will contain L-Threonate, will likely have some ingredients microencapsulated and some not or maybe none is microencapsulated.
I am currently using a prototype with Asc-2P without microencapsulation. Everything was dissolved and application is fine, but I can´t tell for sure if it gets absorbed or not.
Sorry, I can´t tell you concentrations, you have to trust me that I know what I do. You must not be afraid that we may toss in an inferior low concentration because you think L-Threonate may be expensive. It is not expensive, at least not for us. We pay a 24 times lower price for L-Threonate (which includes shipping costs to Germany) than what you guys pay at ka...shop ... (without shipping costs).

[The Mission]

The ingredients are impressive. But I wonder whether they will lose their effectiveness over a short period of time.

Jacob, I can't sign in with my old username. What's up?

TN

[Fizzball]

I guess that's something we'll learn as time goes by.

In terms of a shampoo and conditioner I am very much impressed with the Revita range and would need a lot of convincing to drop it as it has been very good to me so far, I wonder if we could get your professional opinion on the Revita Shampoo and conditioner.

Jacob is on some leave at the moment, he usually takes some time off around this time of the year, sadly the login issue is a consistent problem for some however I am yet to experience it. Fingers crossed i don't.

[Fizzball]

Hi israelite how long have you been using capillogain and is it that thats causing the regrowth or are you on other topicals and oral products?
i been using capillogain for will over a month now! i always had very small hairs but now they are growing. recently i have only been applying 4 topicals! capillogain, ru, vpa, and minox sulfate.

That's quite an arsenal you have there, with so many products its hard for me to take your trial as a complete testimony to this product's effectiveness alone.

[ChemicalBrother]

Hi israelite how long have you been using capillogain and is it that thats causing the regrowth or are you on other topicals and oral products?
i been using capillogain for will over a month now! i always had very small hairs but now they are growing. recently i have only been applying 4 topicals! capillogain, ru, vpa, and minox sulfate.

That's quite an arsenal you have there, with so many products its hard for me to take your trial as a complete testimony to this product's effectiveness alone.

Agree with you Fizzball ...
As much as I want this (Capillogain Tonic) to work (as only topical - (in combination with Fin)) ... I'm still waiting to see positive effects on my own hair.
Been using it 3 weeks now (2 times a day) ... fingers crossed

[israelite]

remmber my hair follicles never died. u can see this from my pics. capillogain is making thosehairs grow longer

[israelite]

Hi israelite how long have you been using capillogain and is it that thats causing the regrowth or are you on other topicals and oral products?
i been using capillogain for will over a month now! i always had very small hairs but now they are growing. recently i have only been applying 4 topicals! capillogain, ru, vpa, and minox sulfate.

That's quite an arsenal you have there, with so many products its hard for me to take your trial as a complete testimony to this product's effectiveness alone.

i agee 100% i think iwill make a list of the people have been using capillogain and post their experience with capillogain. i like the ingredients and the vehicle. i been using for well over a months an i havent even put a dent in the bottle. it will last several months for me

[SyntheseLabRat]

That's quite an arsenal you have there, with so many products its hard for me to take your trial as a complete testimony to this product's effectiveness alone.

I guess he uses VPA only for a very short time but not sure though.