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Dr. Yechiel is the Founder, President, and Director of Research of Elsom Research Co., Inc., maker of the New Equilibrium line of cosmeceuticals which includes the Equisomin Serum anti-aging scalp treatment. He specializes in the biochemistry and biophysics of cellular aging and cell membrane structures, and has developed novel nano-encapsulation and nano-emulsion technologies for topical applications. Dr. Yechiel is also the creator of The Formulator, enabling consumers to select the ingredients for their own custom-made retail-size formulations.
JAY 2005-06-18
hairloss products
Dear Dr. Yechiel, what are your thoughts about Procede and Avacor? how do u compare these two products with Rogaine and propecia? Are they safe enough to use? would You recommend Procede or Avacor to your patients? .. thanks for your time!
Hello Jay,
I am not an M.D., I am a Ph.D. I am a biochemist, which means I do not have patients and I do not recommend medicines, but I can explain the biochemical processes by which medicines operate. I am providing you with scientific information; what you do with the information is your decision.
ProCede is not a medicine and is not claiming to be a medicine. It is a cosmetic product claiming that it produces the appearance of thicker, fuller-looking hair, with results that may be clearly visible in just 48 hours. The word to notice here is appearance; 48 hours is clearly not enough time to regrow hair and so the formula is not intended for hair regrowth, nor does it claim that it is. The possible mechanism of action in the formula is via interference with sulphhydryl bonds between amino acids in the hair by opening them and then closing them in a more bulky rearrangement. It is also possible that sulphhydryl bonds in the scalp are affected, diluting the fiber network in the scalp. There is a regrowth philosophy claiming that this can free the pathway for hairs that are trying to grow out through the scalp but are mechanically blocked. Overall, this product can make your hair fragile and brittle for a while and many hairs can break without recombining.
Topical Avacor contains minoxidil as an active ingredient; because minoxidil is a medicine, Avacor is a medicine. Topical Rogaine also contains minoxidil which improves blood flow to the scalp. Increased blood flow is speculated as its regrowth mechanism Because minoxidil helps with hair-loss and also improves blood flow to the scalp, therefore poor blood flow to the scalp is speculated to be the cause of hair-loss. Propecia contains finasteride which is an androgen hormone inhibitor. Because finasteride helps with hair-loss and is an androgen hormone inhibitor, androgens, particularly DHT, are speculated to be the cause of hair-loss. Avacor and Rogaine have the same active ingredient but are not the same. The quality of the formulation as a whole and its ability to penetrate the scalp or not to cause irritation is very important. People are also different from each other and some may find one formulation more suitable than the other.
Thank you for your question
Elishalom Yechiel, Ph.D.
President
Elsom Research Co., Inc.
http://www.elsomresearch.com/
http://www.the-formulator.com/
210.493.5225
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