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	Dr. Richard Lee, MD

Dr. Lee is the founder and owner of Regrowth LLC, a company based in Los Angeles and dedicated to the treatment of hair loss. He has been developing innovative products and treating hair loss sufferers for the past 16 years. Dr. Lee is the creator of the Xandrox line of hair loss treatments.

Important Note: Due a busy schedule, Dr. Lee cannot answer any new questions at this time; however, he will be providing high quality answers to questions he receives from his own practice exclusively to Morphollica.com regularly

	Question Asked By

anonymous
2005-09-15

	Question Topic

What are ASCJ products for hair loss?

	Question

What are ASCJ products and why might they become important in the treatment of MPB?

	Answer

They are a group of novel anti-androgens being investigated by the Androscience Corporation in San Diego. ASCJ products have the potential of being safe and very effective topical medications for defeating the action of DHT in the scalp. ASCJ is synthesized from a natural product and promotes the degradation of endogenous androgen receptors. This pharmacological mechanism differs completely from all currently available anti-androgens. In laboratory tests, topically applied testosterone induced inhibition of the hair cycle progression with prolongation of the telogen phase 50% of the time in the mouse model. Whereas anagen conversion was achieved in 100% of the mice given testosterone followed with ASCJ-9. The researchers concluded, These preliminary observations suggest that ASCJ-9 is a potential candidate for effective and safe topical treatment of acne and male pattern baldness.*

Currently, AndroScience is conducting GLP (Good Laboratory Practice) toxicology and accumulating other preclinical data in order to file an IND (Investigational New Drug application) and proceed to Phase I and II clinical studies.

*Ching-Yuan Su Effects of a Novel Anti-androgen on Rodent Models of Acne and Testosterone Dependent Suppression of Hair Cycle presented at the summer session of the American Academy of Dermatology 2005

Richard Lee, M.D.
Regrowth, LLC

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