Verbascoside & dht

[Jacob]

http://www.personalcaremagazine.com/Sto ... Story=6026

Indeed, further to its well known scavenger activity for oxygen and nitrogen free radicals, it also chelates transition metals and inhibits many pro-inflammatory processes. These include the activity of the COX-2 enzyme in macrophagic cells, the inducible nitric oxide synthase gene expression, and the nitric oxide production in endothelial cell lines; it suppresses the release of arachidonic acid and eicosanoid synthesis and inhibits NF-kB activation.16,17,18,19,20,21 A recent result has also shown that verbascoside can also reduce the enzymatic activity of 5-alpha-reductase, the key enzyme involved in the biotransformation of testosterone into dihydrotestosterone (DHT).